WHO guidelines on waist circumference and physical activity and their joint association with cancer risk.

ABSTRACT:

Objective

Low body fat and high physical activity levels are key lifestyle factors in cancer prevention, but the interplay of abdominal obesity and physical activity on cancer risk remains unknown. We explored individual and joint associations of waist circumference and physical activity with cancer risk.

Methods

Using UK Biobank data (n=315 457), we categorised individuals according to WHO guideline thresholds for waist circumference and self-reported physical activity levels. Multivariable-adjusted Cox regression was used to estimate HRs and 95% CIs of total cancer. The reference group comprised individuals with recommended levels of waist circumference (<88 cm for women and <102 cm for men) and physical activity (>10 metabolic equivalent of task hours/week). Furthermore,

SUBMITTER: Bohmann P 

PROVIDER: S-EPMC11874282 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature