A green three-ratio manipulating spectrophotometric approaches for the determination of a binary mixture of pantoprazole and domperidone.

ABSTRACT:

Background

Pantoprazole (PAN) is a proton pump inhibitor used to treat GERD and hyperacidity by suppressing gastric acid secretion, effectively relieving symptoms such as heartburn, acid regurgitation, and indigestion. Domperidone (DOM) is a prokinetic agent that enhances gastrointestinal motility, helping to alleviate nausea, vomiting, and bloating caused by motility disorders. Their combination (Pantosec-D) provides rapid and comprehensive relief from both acid-related and motility-related symptoms, significantly improving patient comfort and quality of life.

Objective

This study aims to develop and validate three eco-friendly spectrophotometric techniques-ratio difference (RD), first derivative (1DD), and mean centering (MC) of ratio spectra-for the simultaneous determina

SUBMITTER: Abuseada HHM 

PROVIDER: S-EPMC11874381 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature