Seroprevalence of Toscana virus in blood donors in mainland Portugal.

ABSTRACT:

Background

Toscana virus (TOSV; Phlebovirus toscanaense), a phlebovirus transmitted by sand flies, is a growing public health concern in the Mediterranean region, with infections often being asymptomatic but potentially leading to neuroinvasive disease. Despite its presence in neighboring countries, data on TOSV seroprevalence in Portugal are limited. This study aimed to estimate the national seroprevalence of TOSV among blood donors in mainland Portugal and explore associations with sociodemographic factors and Leishmania infection.

Methods

A cross-sectional study was conducted using serum samples from 3593 blood donors across mainland Portugal, collected between February and June 2022. Anti-TOSV antibodies were detected via microneutralization assay, and anti-Leishmania an

SUBMITTER: Rocha R 

PROVIDER: S-EPMC11874794 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature