Comparison of the value of FAPI imaging and speckle‑tracking echocardiography in assessment of right ventricular remodeling in pulmonary hypertension.

ABSTRACT:

Purposes

This retrospective study was designed to explore the relationship between right ventricular fibroblast activation measured by fibroblast activation protein inhibitor (FAPI) imaging and myocardial deformation measured by Speckle‑tracking Echocardiography (STE) in patients with pulmonary hypertension (PH).

Methods

Clinical data of PH patients were collected [15 chronic thromboembolic pulmonary hypertension (CTEPH), 4 PAH, 1 PH with unclear and/or multifactorial mechanisms]. All of patients underwent FAPI imaging and echocardiography within one month. FAPI activity of right ventricle higher than that in the blood pool was defined as abnormal. The global and segmental maximum standardised uptake values (SUV_max) of the right ventricle were measured and further

SUBMITTER: Chen BX 

PROVIDER: S-EPMC11874803 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature