The Effect of Anthocyanin Supplementation on Pro-Inflammatory Biomarkers in Patients With Metabolic Disorders: A Grade-Assessed Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction and aim

Patients with metabolic disorders benefit from using anthocyanins. Nevertheless, the findings drawn from extant trials remain contentious. Thus, this meta-analysis evaluated anthocyanin's effect on inflammatory biomarkers in patients with metabolic disorders.

Materials and methods

We comprehensively searched electronic databases, including PubMed, Scopus, Web of Science, and CENTRAL, from their inception to June 14, 2024.

Findings

A total of 11 randomized controlled clinical trials with 14 arms were analyzed. There was no significant effect of anthocyanin supplementation on interleukin (IL)-1β levels (standardized mean difference [SMD] = -0.01, 95% CI: -0.33, 0.31; P = 0.941, I ² = 62.4%, P = 0.031), tumor necrosis

SUBMITTER: Kiadehi FB 

PROVIDER: S-EPMC11874868 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature