Association of timing of surgery and outcomes in preterm infants with surgical necrotizing enterocolitis and intestinal perforation.

ABSTRACT: Background: To investigate the association between the timing of surgery from the day of NEC/SIP diagnosis and clinical outcomes in preterm infants. Study Design: A retrospective cohort study comparing clinical outcomes of infants undergoing laparotomy at three clinically relevant time points (less and more than 48 hours, 96 hours, and 168 hours [7 days]) following NEC/SIP diagnosis. Results: Infants with NEC/SIP (N = 97) receiving surgical invention >96 hours (34/97) had significantly lower gestational age (25.5 weeks [24.0; 26.9] vs 27.0 [25.0; 31.3]; p = 0.006), had lower birth weight (687 grams [600; 902] vs 940 [710; 1495]; p<0.001), had pneumoperitoneum less often on the abdominal x-ray (29.4% vs 57.1%, p = 0.017), had hemorrhagic (

SUBMITTER: Garg PM 

PROVIDER: S-EPMC11875456 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature