Cognitive and academic outcomes in children with myelin oligodendrocyte glycoprotein antibody-associated disease.

ABSTRACT:

Aim

To describe the impact of paediatric myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) on academic and cognitive outcomes.

Method

This was an observational, retrospective, and descriptive single-centre study, carried out on a paediatric case series of children with MOGAD.

Results

A total of 51 patients were included (22 females); their median age was 8 years and the median follow-up duration was 31.1 months (interquartile range 23.5). The most frequent clinical presentation was acute disseminated encephalomyelitis (54.9%), followed by optic neuritis (35.5%). At the last follow-up, regardless of the clinical phenotype at disease onset, 39.5% of patients with MOGAD received academic and educational interventions (p < 0.05 compared to before dis

SUBMITTER: Mittelman A 

PROVIDER: S-EPMC11875521 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature