Effect of immunomodulatory agents on the response to COVID-19 vaccination among patients with neuromuscular diseases: A single center experience.

ABSTRACT: Immunomodulatory agents, commonly used in autoimmune neuromuscular disorders, may significantly attenuate immunological response to vaccines. Yet, the degree to which different classes of these drugs suppress the immune system is unclear. This study aimed to characterize the response to the coronavirus disease 2019 (COVID-19) vaccines among our cohort of patients with neuromuscular diseases, including both patients who are and are not receiving immunomodulatory agents. This was a retrospective chart review of our single-center neuromuscular clinic patients who had undergone semi-quantitative COVID-19 antibody testing. A sum of 111 patients were initially identified, and 44 were excluded because of various reasons (e.g., COVID-19 infection, etc). The remaining 67 patients had undergone anti

SUBMITTER: Hsu J 

PROVIDER: S-EPMC11875606 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature