Biomarkers of peanut allergy in children over time.

ABSTRACT:

Background

Various biomarkers are used to define peanut allergy (PA). We aimed to observe changes in PA resolution and persistence over time comparing biomarkers in PA and peanut sensitised but tolerant (PS) children in a population-based cohort.

Methods

Participants were recruited from the EAT and EAT-On studies, conducted across England and Wales, and were exclusively breastfeed babies recruited at 3 months old and followed up until 7-12 years old. Clinical characteristics, skin prick test (SPT), sIgE to peanut and peanut components and mast cell activation tests (MAT) were assessed at 12 months, 36 months and 7-12 years. PA status was determined at the 7-12 year time point.

Results

The prevalence of PA was 2.1% at 7-12 years. Between 3 and 7-12 year, two children d

SUBMITTER: Foong RX 

PROVIDER: S-EPMC11875691 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature