Comparative Genomic Analysis of Livestock-Derived <i>Campylobacter jejuni</i>: Antimicrobial Resistance, Virulence, Mobile Genetic Elements, and Genetic Relatedness.

ABSTRACT: Campylobacter jejuni is a major cause of foodborne illnesses, and its increasing antimicrobial resistance (AMR) poses serious public health risks. Owing to their high genetic diversity and frequent intraspecific recombination, understanding the virulence traits of Campylobacter remains challenging. We elucidated the resistance and virulence mechanisms of C. jejuni in livestock using comparative genomic and phenotypic analyses. We analyzed C. jejuni strains isolated from chicken meat, chicken slaughterhouses, and dairy cattle farms. High resistance rates were observed for nalidixic acid, ciprofloxacin, and tetracycline. The chicken-derived strains showed significantly higher tetracycline resistance and marginally higher nalidixic acid resistance, whereas the catt

SUBMITTER: An JU 

PROVIDER: S-EPMC11876010 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature