Associations of the Life's Essential 8 with Parkinson's disease: a population-based study.

ABSTRACT:

Background

Parkinson's disease (PD) is a progressive neurodegenerative disorder with increasing global prevalence. This study investigated the association between the American Heart Association's Life's Essential 8 (LE8) and PD prevalence using a large, nationally representative database.

Methods

We analyzed data from 18,277 participants aged 40 years and older from the National Health and Nutrition Examination Survey (NHANES) 2005-2018. LE8 scores were calculated based on diet, physical activity, nicotine exposure, sleep, body mass index, blood lipids, blood glucose, and blood pressure. PD cases were identified through self-reported anti-PD medication use. Multivariate logistic regression models were employed to examine the association between LE8 and PD prevalence, adjusti

SUBMITTER: Zhou C 

PROVIDER: S-EPMC11876173 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature