Nonlinear association between serum 25-hydroxyvitamin D concentrations and lung function in the United States adult population with COPD.

ABSTRACT: Vitamin D has been studied for its potential protective effects against lung function decline in patients with COPD. However, conflicting results exist, the actual effect of vitamin D on lung function remains controversial. This study aimed to determine whether serum 25-hydroxyvitamin D (25-OHD) levels are correlated with lung function in community-dwelling individuals with COPD. We used data from the National Health and Nutrition Examination Survey (NHANES) to explore the relationship between serum 25-OHD concentration and the severity of airflow obstruction. Multivariable logistic regression, stratified analysis with interaction, restricted cubic splines (RCS), and threshold effect analysis were used to investigate the association between serum 25-OHD concentration and lung function.A to

SUBMITTER: Han Z 

PROVIDER: S-EPMC11876368 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature