Hepatocyte growth factor and B-type natriuretic peptide as independent predictors of mortality in HFpEF patients.

ABSTRACT:

Background

Heart failure with preserved ejection fraction (HFpEF) is a common and heterogeneous syndrome with high mortality and morbidity. However, few studies have evaluated the relationship between biomarkers and subsequent outcomes in HFpEF patients.

Objective

To assess the association between plasma hepatocyte growth factor (HGF) levels and all-cause mortality in HFpEF patients.

Methods

This was a retrospective cohort study of 412 HFpEF patients who were hospitalized in the Department of Cardiology of the First Affiliated Hospital of Anhui Medical University from November 2020 to November 2021. The patients were divided into two groups according to the 24-month follow-up results: deceased (82 cases) and survivors (330 cases). The primary outcome was all-cause mor

SUBMITTER: Chen HL 

PROVIDER: S-EPMC11876389 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature