Right atrial strain in Anderson-Fabry disease.

ABSTRACT:

Background

To date, only limited data are available on right atrium (RA) morphofunctional remodeling in Fabry disease (FD).

Purpose

We aimed to investigate RA structural and functional remodeling in patients with FD vs. healthy controls using 2D speckle tracking echocardiography (STE) and to explore whether any differences exist in FD patients with and without left ventricular hypertrophy (LVH).

Methods

We prospectively enrolled patients with FD and controls matched for age, sex, and cardiovascular risk factors. Patients with FD were divided in two groups according to the presence/absence of LVH (LVH+: left ventricular wall thickness >12 mm). All patients underwent standard echocardiography and STE analysis investigating the mechanics of all cardiac chambers, includin

SUBMITTER: Lillo R 

PROVIDER: S-EPMC11876412 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature