Gender-neutral vs. gender-specific strategies in school-based HPV vaccination programs: a systematic review and meta-analysis.

ABSTRACT:

Introduction

This systematic review and meta-analysis evaluated whether gender-neutral (GN) or gender-specific (GS) strategies more effectively enhanced knowledge, intention, and uptake of HPV vaccination among students in educational settings.

Methods

A comprehensive literature search of PubMed, Scopus, Web of Science, and Cochrane Library identified 17 randomized controlled trials encompassing 22,435 participants (14,665 females, 7,770 males). Random-effects models were used to calculate standardized mean differences (SMDs) for knowledge and intention, and risk differences for vaccination uptake.

Results

GN strategies achieved higher improvements in knowledge (SMD = 0.95) and intention (SMD = 0.59) compared with GS (SMD = 0.68 for knowledge, SMD = 0.14 for intention

SUBMITTER: Chandeying N 

PROVIDER: S-EPMC11876415 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature