High-grade intraepithelial lesions of the anus-patience: A road to wisdom.

ABSTRACT:

Aim

The progression of high-grade squamous intraepithelial lesions (HSILs) to anal cancer is feared. Data on the remission of HSILs are scarce, and factors associated with remission have not been identified. The aims of this study were to determine the rate of remission of HSILs and to identify factors associated with remission.

Method

Consecutive patients with HSILs referred to a tertiary proctology unit for monitoring were identified in a prospective database. Clinical data, as well as cytological, histological and treatment data, were recorded. The remission of HSILs was defined by the normality of the macroscopic examination and the normal histology and/or cytology of at least two consecutive samples.

Results

Overall, 144 patients with HSILs were followed for 4.1

SUBMITTER: Gouriou C 

PROVIDER: S-EPMC11876482 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature