Overall and Cause-Specific Mortality Among Patients With Cutaneous T-Cell Lymphoma in the United States.

ABSTRACT:

Introduction

Little is known about long-term outcomes and causes of death for individuals with cutaneous T-cell lymphoma.

Methods

We used SEER-18 registry data to examine outcomes among 9886 adults with mycosis fungoides (MF), Sézary syndrome (SS), primary cutaneous anaplastic large cell lymphoma (pcALCL), and subcutaneous panniculitis-like T-cell lymphoma (SPTCL) diagnosed from 2000 to 2018. We calculated overall survival (Kaplan-Meier method), standardized mortality ratios (SMRs), absolute excess risk (AER) of death, and cumulative incidence of cause-specific mortality.

Results

Individuals with CTCL were at increased risk of all-cause mortality relative to age-matched controls, with SMR ranging from 1.57 (95% CI: 1.49-1.65) in MF to 5.61 (95% CI: 4.65-6.7) in SS. Th

SUBMITTER: Shea L 

PROVIDER: S-EPMC11876778 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature