Vaccination and Seasonality as Risk Factors for Development of Meningoencephalitis of Unknown Origin in 172 Dogs.

ABSTRACT:

Background

Meningoencephalitis of unknown origin (MUO) is a neuroinflammatory disease that is suspected to be immune-mediated. Vaccination and season inconsistently have been reported as risk factors for development of MUO in dogs, but limited prospectively collected data is available to evaluate these potential risk factors.

Objective

Prospectively evaluate the association between vaccination and season and the development of MUO in dogs.

Animals

A total of 172 client-owned dogs diagnosed with MUO.

Methods

Dogs were enrolled prospectively from August 2021 through July 2023. Signalment, body weight, vaccination history, and season of onset of neurologic signs were recorded. The incidence rate ratio (IRR) of MUO within various post-vaccination windows was statis

SUBMITTER: Johnson MK 

PROVIDER: S-EPMC11877001 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature