Diameter thresholds for pure ground-glass pulmonary nodules at low-dose CT screening: Chinese experience.

ABSTRACT:

Background

Limited research exists on screening thresholds for low-dose CT in detecting malignant pure ground-glass lung nodules (pGGNs) in the Chinese population.

Materials and methods

A retrospective analysis of the Guangzhou Lung-Care programme was conducted, retrieving average transverse diameter, location, histopathology, frequency and follow-up intervals. Diagnostic performances for 'lung cancers' were evaluated using areas under the curve (AUCs), decision curve analysis (DCA), sensitivities and specificities, with thresholds ranging from 5 mm to 10 mm. We divide malignant pGGNs into three groups: (1) minimally invasive adenocarcinoma (MIA) and invasive adenocarcinoma (IA), (2) atypical adenomatous hyperplasia (AAH) and adenocarcinoma in situ (AIS) and MIA and IA and (

SUBMITTER: Ye W 

PROVIDER: S-EPMC11877040 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature