Doxycycline Postexposure Prophylaxis and Bacterial Sexually Transmitted Infections Among Individuals Using HIV Preexposure Prophylaxis.

ABSTRACT:

Importance

Doxycycline postexposure prophylaxis (doxyPEP) has been shown to decrease the incidence of bacterial sexually transmitted infections (STIs) among people assigned male sex at birth in clinical trials, but data from clinical practice are limited.

Objective

To describe early uptake of doxyPEP and evaluate changes in STI incidence following doxyPEP initiation.

Design, setting, and participants

This retrospective cohort study of adults (aged ≥18 years) dispensed HIV preexposure prophylaxis (PrEP) at Kaiser Permanente Northern California during November 1, 2022, to December 31, 2023, examined electronic health record data to compare HIV PrEP users dispensed and not dispensed doxyPEP and rates of bacterial STIs before and after starting doxyPEP. Individuals were f

SUBMITTER: Traeger MW 

PROVIDER: S-EPMC11877173 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature