Outcomes of a Population-Based Congenital Cytomegalovirus Screening Program.

ABSTRACT:

Importance

Detection of congenital cytomegalovirus (cCMV) infection has previously relied on targeted screening programs or clinical recognition; however, these approaches miss most cCMV-infected newborns and fail to identify those infants who are asymptomatic at birth but at risk for late-onset sensorineural hearing loss.

Objective

To determine the feasibility of using routinely collected newborn dried blood spots (DBS) in a population-based cCMV screen to identify infants at risk for hearing loss and describe outcomes of infants screened.

Design, setting, and participants

This diagnostic study of a population-based screening program in Ontario, Canada, took place from July 29, 2019, to July 31, 2023. All newborns with a DBS sample collected as part of routine care w

SUBMITTER: Dunn JKE 

PROVIDER: S-EPMC11877178 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature