Variations in sex differences in major cardiometabolic risk factors by age and menopause status: results from the UK Biobank.

ABSTRACT:

Background

Sex differences have not been fully explored for certain risk factors or by age or age-related factors, such as menopause. We addressed this issue in a large population cohort.

Methods

UK Biobank participants with ≥1 risk factor measured at baseline were included. We assessed sex differences, by age and menopausal status, in prevalence, treatment and control of cardiometabolic risk factors.

Results

501 389 adults (54.4% women, mean age 56.6 (SD 8.1) years) were included. Mean risk factor levels that were lower in women than men include systolic blood pressure (women-to-men difference: -5.6 mm Hg), diastolic blood pressure (-3.4 mm Hg), body mass index (-0.75 kg/m²), waist circumference (-12.2 cm), triglycerides (0.34 mmol/L), glycated haemoglobin

SUBMITTER: Kelly RK 

PROVIDER: S-EPMC11877249 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature