Accuracy of individual signs and symptoms and case definitions for the diagnosis of influenza in different age groups: a systematic review with meta-analysis.

ABSTRACT:

Objective

The objective of this study is to perform a comprehensive systematic review and meta-analysis of the accuracy of signs, symptoms and case definitions for the diagnosis of influenza.

Design

Systematic review and meta-analysis of diagnostic accuracy.

Setting

Inpatient or outpatient setting.

Participants

Three databases (PubMed, CINAHL and EMBASE) were searched through February 2024 for studies of clinical diagnosis of influenza using prospective data collection and a high-quality reference standard. Data were abstracted by researchers working in parallel and resolving discrepancies by discussion.

Primary and secondary outcome measures

Quality was assessed using QUADAS-2. Summary estimates (or ranges) of sensitivity and specificity, likelihood rat

SUBMITTER: Ebell MH 

PROVIDER: S-EPMC11877276 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature