Supradecoration induced homogenous electrochemical sensing: development of Ru(ii) half sandwich complex as isoniazid and rifampicin dual sensor.

ABSTRACT: Homogenous electrochemical sensing using unmodified electrodes remove electrode fabrication challenges and prove effective for detecting sensitive bio-analytes without chances of surface degradation. This work envisages design and optimization of a ruthenium(ii) half-sandwich complex as supradecorated homogeneous electrochemical sensor for simultaneous detection of rifampicin (RIF) and isoniazid (INH) as first-line anti-tuberculosis drugs in aqueous environments. The electrochemical profile of GCE/ruthenium(ii) half-sandwich complex sensor was analyzed using cyclic voltammetry, differential pulse voltammetry and electrochemical impedance spectroscopy (EIS). The results indicate significant electrochemical parameters corroborating enhanced sensing propensity of GCE/ruthenium(ii) half-sandwi

SUBMITTER: Mustafa M 

PROVIDER: S-EPMC11877425 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature