Galvanic vs. pulsatile effects on decision-making networks: reshaping the neural activation landscape.

ABSTRACT: Objective. Primarily due to safety concerns, biphasic pulsatile stimulation (PS) is the present standard for electrical excitation of neural tissue with a diverse set of applications. While pulses have been shown to be effective to achieve functional outcomes, they have well-known deficits. Due to recent technical advances, galvanic stimulation (GS), delivery of current for extended periods of time (>1 s), has re-emerged as an alternative to PS.Approach. In this paper, we use a winner-take-all decision-making cortical network model to investigate differences between pulsatile and GS in the context of a perceptual decision-making task.Main results. Based on previous work, we hypothesized that GS would produce more spatiotemporally distributed, network-sensitive neural r

SUBMITTER: Adkisson PW 

PROVIDER: S-EPMC11877455 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature