Single versus dual antiplatelet therapy impact on coagulation/thrombosis post PAD revascularization.

ABSTRACT:

Objective

To evaluate and compare the impact of single- versus dual-antiplatelet (SAPT vs DAPT) therapy on coagulation profiles and postoperative outcomes in patients with peripheral arterial disease (PAD).

Methods

Patients with PAD undergoing lower extremity revascularization from December 2020 to August 2023 were prospectively enrolled in this cohort study and followed for one year to record the incidence of thrombotic events (TEs). These events include arterial graft/stent occlusion or stenosis, as identified through Doppler ultrasonography or angiography. Patients were categorized by type of intervention (open vs. endovascular) and further stratified by thromboprophylaxis regimen (SAPT vs DAPT). Descriptive statistics were conducted to characterize each group. Difference

SUBMITTER: Rodriguez Alvarez AA 

PROVIDER: S-EPMC11877524 | biostudies-literature | 2025 Jan-Mar

REPOSITORIES: biostudies-literature