Association of triglyceride-glucose index with bone mineral density and fracture: a systematic review.

ABSTRACT:

Background and aim

Studies have found inconsistent results regarding triglyceride-glucose (TyG) index and bone health. This systematic review aims to synthesize the existing evidence on the association between the (TyG) index, bone mineral density (BMD), and bone fractures.

Method

A comprehensive search of PubMed, Scopus, Web of Science, and Embase databases was performed for studies published up to December 26, 2024. Inclusion criteria encompassed human studies examining the TyG index in relation to BMD or fractures. The risk of bias was assessed using the Newcastle-Ottawa Scale (NOS). Data synthesis included both qualitative and descriptive statistical analyses.

Results

From 201 studies identified, 12 met the inclusion criteria comprising 817,242 participants. Most

SUBMITTER: Yousefiasl M 

PROVIDER: S-EPMC11877733 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature