The origin and dissemination of HIV-1 subtype B on Hainan Island, South China, 2007-2024.

ABSTRACT:

Background

HIV-1 subtype B, introduced to mainland China at an early stage, rapidly spread among commercial plasma donors and heterosexuals (HETs) during the 1990s. It was first identified in Hainan, which has a population of 10 million, in 2007. Nevertheless, there is a paucity of data about the molecular-epidemiological characteristics, spatial origins, and transmission patterns of this strain on the island of China.

Methods

Pol sequences for HIV-1 subtype B from Hainan Island (2007-2024) were obtained from our research and global databases. An analysis of phylogenetic data, molecular clock models, and a Bayesian coalescent-based approach was performed to investigate how HIV-1 subtype B was introduced and disseminated on this island.

Results

A total of 76 sequences

SUBMITTER: Lu C 

PROVIDER: S-EPMC11877774 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature