Population based registry study on large B-cell lymphoma mortality and morbidity in Finland.

ABSTRACT:

Background

Large B-cell lymphomas (LBCLs) form a notable subgroup of lymphomas; however, their associated long-term comorbidities and mortality rates remain under-researched in real-world settings.

Material and methods

This nationwide Finnish population-based matched cohort study included virtually all LBCL patients (N = 7,019) diagnosed from 2008 to 2019, alongside age, sex, and region-matched controls (1:1 ratio) without lymphoma. Diagnoses of LBCLs were obtained from the Finnish Cancer Registry, with data linked to additional nationwide registries. Baseline characteristics were summarised using descriptive statistics. Overall survival (OS) was estimated using the Kaplan-Meier method, while Cox regression was used to analyse factors associated with OS and evaluate the risk

SUBMITTER: Anttalainen A 

PROVIDER: S-EPMC11877859 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature