Associations of preconception air pollution exposure with growth trajectory in young children: A prospective cohort study.

ABSTRACT: Gestational air pollution exposure was associated with childhood obesity. However, little is known about the effect of air pollution exposure during the preconception period, a critical window when environmental exposures may affect body growth trajectory and increase obesity risk. We conducted a population-based prospective cohort study of preconception women and their newborn children followed until 2 years old from metropolitan Shanghai, China to investigate the impact of preconception air pollution on childhood weight and body mass index (BMI) growth trajectories. Exposures to PM_2.5, PM₁₀, and NO₂ during 3 months before conception and each trimester of pregnancy were estimated using high-resolution spatiotemporal models matched at residential addresses.

SUBMITTER: Liao J 

PROVIDER: S-EPMC11878012 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature