Hemostatic Outcome Definitions in Pediatric Extracorporeal Membrane Oxygenation: Challenges in Cohorts From Rotterdam (2019-2023) and Melbourne (2016-2022).

ABSTRACT:

Objectives

To determine if a priori standardization of outcome hemostatic definitions alone was adequate to enable useful comparison between two cohorts of pediatric extracorporeal membrane oxygenation (ECMO) patients, managed according to local practice and protocol.

Design

Comparison of two separate prospective cohort studies performed at different centers with standardized outcome definitions agreed upon a priori.

Setting

General and cardiac PICUs at the Royal Children's Hospital (RCH) in Melbourne, Australia, and the Sophia Children's Hospital (SCH) in Rotterdam, The Netherlands.

Patients

Children (0-18 yr old) undergoing ECMO.

Interventions

None.

Measurements and main results

Although outcome definitions were standardized a priori, the interp

SUBMITTER: Drop J 

PROVIDER: S-EPMC11878593 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature