Evaluating sensitivity and specificity of the DPP Vet TB assay in badgers using Bayesian latent class models.

ABSTRACT: In the UK and Ireland, the European badger is the main wildlife reservoir for Mycobacterium bovis (M. bovis), the causal agent of bovine tuberculosis (bTB). The ability to diagnose M. bovis infection in badgers is critical to understanding the epidemiology of the infection in this species and for informing control strategies. In this study we determined the sensitivity and specificity of a lateral flow assay (Dual Path Platform (DPP) VetTB assay) to identify infected live badgers using two blood sample types: fresh whole blood (suitable for immediate testing in the field without further processing) and serum (which can be stored frozen for batch testing). Two measures were used for the interpretation of test results: qualitative visual interpretation and quantitative measurement using an o

SUBMITTER: Jinks RC 

PROVIDER: S-EPMC11878917 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature