Prophylactic treatment of FSGS recurrence in patients who relapsed on a previous kidney graft.

ABSTRACT:

Background

Recurrence of focal segmental glomerulosclerosis (FSGS) is common after kidney transplantation and is classically associated with a significant decrease in graft survival. A major risk factor is a prior history of FSGS recurrence on a previous graft. This analysis reports the impact of a prophylactic treatment of FSGS recurrence in very high-risk patients who experienced a recurrence on a previous graft.

Methods

We performed a retrospective multicentre observational study in 25 French transplantation centres. The inclusion criteria were patients aged more than 18 years who had undergone kidney transplant between 31 December 2004 and 31 December 2020, and who had a history of FSGS recurrence on a previous graft.

Results

We identified 66 patients: 40 received

SUBMITTER: Uro-Coste C 

PROVIDER: S-EPMC11879060 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature