Neuroimaging-Based Responses to Blood Pressure Augmentation in Acute Ischaemic Stroke: A Systematic Review.

ABSTRACT:

Introduction

In acute ischaemic stroke, the key treatment to reduce infarct growth is reperfusion, achieved through thrombolysis, endovascular thrombectomy, or endogenous reperfusion. Prior to definitive reperfusion therapy, blood pressure augmentation may enhance cerebral perfusion and reduce interim infarct growth. This study aimed to summarise the existing evidence from randomised controlled trials on the use of imaging for patient selection and the assessment of blood pressure augmentation in acute ischaemic stroke.

Methods

A systematic review was conducted of the databases PubMed, Embase, and Cochrane Library in accordance with the PRISMA guidelines. The systematic review was prospectively registered on PROSPERO.

Results

Initial searches returned 266 results, of

SUBMITTER: Goh R 

PROVIDER: S-EPMC11879148 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature