Melatonin may protect the gastrointestinal system from cadmium chloride toxicity during pregnancy.

ABSTRACT: Cadmium is absorbed into the body through food consumption. Since food intake increases during pregnancy, Cadmium consumption from food also increases. Melatonin, secreted by the pineal gland, is an antioxidant hormone with therapeutic effects. This research aims to reveal how Cadmium Chloride (CdCl₂) affects antioxidant capacity by histological and biochemical methods and to test the effect of Melatonin in treating CdCl₂-induced lesions in pregnant mice's stomach and small intestine. Control, CdCl₂, Melatonin, and CdCl₂ + Melatonin groups were created using pregnant mice (n: 6). CdCl₂ (2 mg/kg/bw) and Melatonin (3 mg/kg/bw) were administered. The investigation was terminated after birth. Stomach and small intestine tissues were pull o

SUBMITTER: Sensoy E 

PROVIDER: S-EPMC11879212 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature