Different temporal relationship between sex hormones and sleep status in midlife women: a longitudinal cohort study.

ABSTRACT:

Background

Fluctuation in sex hormones and the occurrence of sleep disturbance are 2 major health challenges among midlife women. However, the temporal relationship between them remains unclear.

Methods

This study included 2488 females (mean ± SD age, 49.0 ± 2.70 years) with an average follow-up of 6.95 years. We constructed a composite score by summing items related to sleep problems to reflect the comprehensive sleep status of the participants in the Study of Women's Health Across the Nation. Cross-lagged path analysis was used to examine the temporal relationship between sex hormones and sleep status. Sensitivity analyses were conducted in nonoverweight and overweight groups and adjusted for vasomotor symptoms in the main model.

Aim

In this study, we aimed to exami

SUBMITTER: Ma D 

PROVIDER: S-EPMC11879248 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature