Joining forces: a complex cardio-obstetrics case report of severe ergometrine-induced vasospasm.

ABSTRACT:

Background

Ergometrine is part of the current guideline-directed management of post-partum haemorrhage (PPH). However, it is also a potent vasoconstrictor capable of causing significant coronary artery vasospasm in susceptible individuals.

Case summary

A 31-year-old primigravida suffered from post-partum haemorrhagic shock and disseminated intravascular coagulation following vaginal delivery. She was urgently resuscitated with intravenous fluids and blood products. Intramuscular ergometrine was administered, and surgery was required due to retained placenta. Two days later upon extubation, she demonstrated symptoms of speech apraxia. Brain magnetic resonance imaging (MRI) revealed extensive cerebral and cerebellar infarction with subcortical sparring. Her electrocardiogram s

SUBMITTER: Radhakrishna A 

PROVIDER: S-EPMC11879452 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature