The association between long-term PM2.5 exposure and risk for pancreatic cancer: an application of social informatics.

ABSTRACT: There is a profound need to identify modifiable risk factors to screen and prevent pancreatic cancer. Air pollution, including fine particulate matter (PM2.5), is increasingly recognized as a risk factor for cancer. We conducted a case-control study using data from the electronic health record (EHR) of Duke University Health System, 15-year residential history, NASA satellite fine particulate matter (PM2.5), and neighborhood socioeconomic data. Using deterministic and probabilistic linkage algorithms, we linked residential history and EHR data to quantify long-term PM2.5 exposure. Logistic regression models quantified the association between a 1 interquartile range (IQR) increase in PM2.5 concentration and pancreatic cancer risk. The study included 203 cases and 5027 controls (median age o

SUBMITTER: Bhavsar NA 

PROVIDER: S-EPMC11879496 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature