The impact of bicuspid valve morphology on the selection of transcatheter aortic valve implantation devices: an <i>in silico</i> study.

ABSTRACT:

Aims

Bicuspid aortic valve (BAV) represents a challenge for transcatheter aortic valve implantation (TAVI). Few data are reported about the procedural implications of BAV using different self-expandable devices. The aim of this study is to investigate how BAV and tricuspid aortic valve (TAV) morphologies influence device selection and their impact on the potential development of post-operative conduction disturbances, using a novel in silico approach.

Methods and results

Five patients with BAV undergoing TAVI were enrolled. TAVs were virtually modelled within each BAV patient-specific anatomy, resulting in 10 virtual patients. Acurate Neo2 and Evolut R implantations were subsequently simulated across all cases. Post-implantation stresses exerted on both the stent and

SUBMITTER: Grossi B 

PROVIDER: S-EPMC11879518 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature