Doxycycline Postexposure Prophylaxis for Bacterial STIs: Prescribing Patterns, Use, Short-term Outcomes Among 2083 Patients in a Los Angeles Federally Qualified Health Care Program, and Implications for Widespread Use.

ABSTRACT:

Background

Rates of bacterial sexually transmitted infections (STIs) have risen dramatically over the past decades. Doxycycline postexposure prophylaxis (DP) is a novel intervention to prevent bacterial STIs. Recent randomized controlled clinical trials reported high DP efficacy at preventing syphilis and chlamydia in cisgender men who have sex with men and transgender women.

Methods

We abstracted data from the electronic health records of 2083 patients at the Los Angeles LGBT Center (the Center) who were prescribed DP between 2019 and June 2024. Patient information included race, income, gender, sex, DP prescriptions, and STI tests dating back to 1998.

Results

More than half of the patients prescribed DP at the Center were White, and 48.1% were between 31 and 40 year

SUBMITTER: Osmundson J 

PROVIDER: S-EPMC11879542 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature