Negative Schizotypy Associated With Weaker Intersubject Correlation in Dynamic Functional Connectivity During Empathic Accuracy Task.

ABSTRACT:

Background and hypothesis

Previous studies on Empathic Accuracy Task (EAT) suggested patients with schizophrenia exhibited altered brain activations in the precuneus, middle frontal gyrus, and thalamus. However, it remains unclear whether individuals with schizotypy would exhibit similar alterations of brain activations associated with EAT. This study aimed to examine the relationships between schizotypy and intersubject correlation (ISC) during EAT.

Study design

Forty-seven college students undertook the Chinese version of EAT in a 3T MRI scanner. The Chapman Social Anhedonia Scale (CSAS) and Perceptual Aberration Scale (PAS) were used to capture negative and positive schizotypy, respectively. We adopted GLM analysis, ISC analyses of brain activation, and dynamic functional

SUBMITTER: Hu DD 

PROVIDER: S-EPMC11879588 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature