The inflammatory response to Escherichia coli lipopolysaccharide is mitigated by in ovo delivery of carvacrol in broiler chicks.

ABSTRACT: The broiler chickens' immune system fully develops a few weeks after hatching, leaving them susceptible to disease during the early post-hatching phase. This study investigated effects of in ovo delivery of carvacrol on the expression of immune-related genes following an Escherichia coli lipopolysaccharide (LPS) challenge at d7 post-hatch. The experiment was designed as a 2 × 2 factorial arrangement with two in ovo treatments (saline or carvacrol) and two LPS challenged groups (yes or no): (1) saline + no challenge (control), (2) saline + LPS, (3) carvacrol + no challenge, (4) carvacrol + LPS. Hatchability and performance parameters were determined before, and organ weights after the LPS challenge. Immune-related gene expression was assessed in the jejunum and spleen post-challenge. At d7,

SUBMITTER: Meijer MMY 

PROVIDER: S-EPMC11879691 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature