Association between relative fat mass and gallstones: a cross-sectional study based on NHANES 2017-2020.

ABSTRACT:

Background

Gallstones are a common gastrointestinal disease worldwide, associated with significant public health burdens. Obesity and fat distribution are recognized as major risk factors for gallstone formation, yet traditional anthropometric indices such as BMI and WC have limitations in reflecting fat distribution and its metabolic consequences. Relative Fat Mass (RFM), a novel anthropometric index, may provide more accurate predictions of gallstone risk, but its association with gallstone formation remains underexplored.

Methods

This study utilized data from NHANES 2017-2020, including 6,084 participants aged ≥20 years, to investigate the relationship between RFM and gallstone risk. Multivariable logistic regression and smooth curve fitting were used to assess this assoc

SUBMITTER: Gao C 

PROVIDER: S-EPMC11879834 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature