Comparison of incidence trends of early-onset and late-onset type 2 diabetes in the Asia-Pacific region, 1990-2021: a join point regression analysis based on the global burden of disease study 2021.

ABSTRACT:

Introduction

This study evaluated the incidence trends of early-onset (diagnosed at ages 15-39) and late-onset (diagnosed at age 40 and above) type 2 diabetes mellitus (T2DM) in the Asia-Pacific region, including the World Health Organization (WHO) South-East Asia Region (SEARO) and Western Pacific Region (WPRO), and assessed the impact of the COVID-19 pandemic.

Methods

Using data from the Global Burden of Diseases Study (GBD) 2021, we analyzed trends in age-standardized incidence rate (ASIR) using Join point regression to determine annual percentage change (APC). To assess the pandemic's impact, we calculated excess incidence for 2020 and 2021 by subtracting predicted ASIR from observed ASIR.

Results

In recent years, particularly during the COVID-19 pandemic, the ASI

SUBMITTER: Lin C 

PROVIDER: S-EPMC11879835 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature