Molecular epidemiology of <i>Neisseria gonorrhoeae</i> isolates in Russia, 2015-2023: current trends and forecasting.

ABSTRACT:

Introduction

The emergence of multidrug resistance in N. gonorrhoeae is a serious global problem, and gonorrhea may soon become an incurable disease. The aim of the study was to characterize the N. gonorrhoeae population in Russia from 2015 to 2023 and predict the potential spread of the most concerning clones.

Methods

A total of 996 N. gonorrhoeae isolates were examined during the analyzed period. Ceftriaxone and azithromycin susceptibility testing were performed using the agar dilution method. Microarray-based assays and sequencing were employed to identify the genotypes and genetic markers of antimicrobial resistance.

Results

No ceftriaxone-resistant isolates were found in Russia, however, the number of isolates with reduced susceptibility to c

SUBMITTER: Kandinov I 

PROVIDER: S-EPMC11879935 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature