Add-on effects of total glucosides of paeony on conventional therapies for psoriasis: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Psoriasis is an inflammatory and recurrent dermatological disease that is associated with multiple comorbidities. Conventional psoriasis therapies such as acitretin capsule and narrow-band ultraviolet B radiation (NB-UVB) are prone to decreased efficacy and adverse events in long-term application. Total glucosides of paeony (TGP), a plant extract from Radix Paeoniae Alba, are commonly used in conjunction with conventional therapies for psoriasis. This study aims to elucidate the add-on effect of TGP on conventional therapies in the treatment of psoriasis.

Methods

Seven databases were searched from their inception to March 2024. Randomized controlled trials (RCTs) using TGP in conjunction with conventional therapies for psoriasis were included. The Risk of Bias 2.0

SUBMITTER: Li Z 

PROVIDER: S-EPMC11880009 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature