Association between systemic immune-inflammation index and central obesity in pediatric populations: a cross-sectional and cohort study.

ABSTRACT:

Background

Central obesity in children represents a significant public health concern due to its strong association with an elevated risk of metabolic and cardiovascular disorders. The systemic immune inflammation index (SII) has been implicated in the pathophysiology of obesity-related chronic inflammation. Despite its potential relevance, the specific relationship between central obesity and SII in the pediatric population remains insufficiently explored. The objective of this study was to examine the relationship between SII and central obesity, with a particular focus on the potential of SII as a predictor of central obesity and a means of preventing obesity at an early stage of life.

Methods

Waist-to-height ratio (WHtR), subcutaneous fat, and visceral fat were employed

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC11880016 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature