Actinobacteria Warfare Against the Plant Pathogen Sclerotinia sclerotiorum: 2,4,6-Trimethylpyridine Identified as a Bacterial Derived Volatile With Antifungal Activity.

ABSTRACT: Bacteria and fungi produce a wide range of specialised metabolites, including volatile organic compounds (VOCs) that can act as signals or act directly to inhibit niche-competing microbes. Despite their ecological importance, most VOCs involved as signalling compounds remain uncharacterised. We have previously screened a collection of Actinobacteria strains sourced from Western Australia for their ability in vitro to suppress the growth of plant fungal pathogens. Here we explored the potential of four of the most active strains to produce antifungal metabolites by growing the strains on a range of nutrient-containing media. A casein-based (CYPS) culture medium was found to induce the production of antifungal compounds with high activity against Sclerotinia sclerotiorum, a major necrotrophi

SUBMITTER: Belt K 

PROVIDER: S-EPMC11880119 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature