On-the-fly resolution enhancement in X-ray protein crystallography using electric field.

ABSTRACT: X-ray crystallography has tremendously served structural biology by routinely providing high-resolution 3D structures of macromolecules. The extent of information encoded in the X-ray crystallography is proportional to which resolution the crystals diffract and the structure can be refined to. Therefore, there is a continuous effort to obtain high-quality crystals, especially for those proteins, which are considered difficult to crystallize into high-quality protein crystals of suitable sizes for X-ray crystallography. Efforts in enhancing the resolution in X-ray crystallography have also been made by optimizing crystallization protocols using external stimuli such as an electric field and magnetic field during the crystallization. Here, we present the feasibility of on-the-fly post-crysta

SUBMITTER: Khakurel KP 

PROVIDER: S-EPMC11880155 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature