Talking during walking: the diagnostic potential of turn dynamics in Alzheimer's disease, mild cognitive impairment and cognitive aging.

ABSTRACT:

Background

While gait analysis is well-documented, turn performance-which is a more complex task and involves multiple brain regions-has been less explored. This study aims to assess the diagnostic potential of turn dynamics as a novel tool for detecting cognitive decline.

Methods

We recruited 75 participants, including 26 neurotypical (NT) older adults, 25 with amnestic mild cognitive impairment (aMCI), and 24 with mild Alzheimer's disease (AD). Participants completed a dual-task walk and turn (DTWT) test using a dual Kinect setup while counting backwards by ones. Key measures analyzed included spatial-temporal parameters of gait and turn dynamics. Statistical analyses including analyses of variance and linear regression were performed to identify key features as well as to

SUBMITTER: Mohammadi H 

PROVIDER: S-EPMC11880252 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature